To sculpt a 3D model with modifiers, start with a low-poly base mesh and use non-destructive modifiers (e.g., Subdivision Surface for smoothing, Dynamic Topology for adaptive detail) to shape and add detail—keeping edits flexible.
Modifiers let you adjust without permanent changes. For example, sculpt a character’s arm by using Subdivision to soften the base, then Dynamic Topology to add muscle definition only where you brush. Toggle modifiers off anytime to edit the original mesh.
Beginners can try Blender’s simple workflow: Add Subdivision to a sphere, sculpt a basic head, and adjust the modifier’s "Levels Viewport"—see how smoothness affects your work without overcomplicating the mesh.